Our research focuses on the physiological, pharmacological and anatomical bases of synaptic transmission, with a particular emphasis on cellular substrates of pathological conditions in the Central Nervous System (CNS).
We use a wide array of approaches, including:
- electrophysiological recording in vivo (micro-optrodes) and in vitro (patch clamp in slices)
- multiphoton and other non-linear imaging techniques
- time-resolved fluorescence microscopy
- in vivo optogenetics
- tissue-based biochemical analysis
- neural tracing and immunocytochemistry
- and computational approaches.
The lab is also actively involved in the development of novel photonics technique development, including
- fluctuation analysis of fluorescent signals
- fibre optic-based probe development
- novel microscopy techniques
- and neural modeling approaches