Nov
30
2003
By Julie
2003: Découverte d'un mécanisme expliquant la douleur chronique
http://www.scom.ulaval.ca/Au.fil.des.evenements/2004/01.22/science.html
For the discovery that the pain hypersensitivity of people suffering from neuropathic pain could be due to a reversal of the mechanisms that suppress pain signals in the spinal cord.
Original research article:
Coull JA, Boudreau D, Bachand K, Prescott SA, Nault F, Sík A, De Koninck P, De Koninck Y. Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain. Nature. 2003 Aug 21;424(6951):938-42.
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