The Journal of Neuroscience has recently featured on its front page a figure from an article De Koninck laboratory members contributed to. The article studies the localisation of a specific receptor on neurons, the Coxsackievirus Adenovirus Receptor (CAR), in healthy brains, but also during development and in neurodegenerative disease conditions. The study suggests CAR has a role in adult neurogenesis, synapses, and plasticity in the hippocampus.
View the about the cover section: http://www.jneurosci.org/content/36/37.cover-expansion
Read the full article here: Zussy C, Loustalot F, Junyent F, Gardoni F, Bories C, Valero J, Desarménien MG, Bernex F, Henaff D, Bayo-Puxan N, Chen JW, Lonjon N, de Koninck Y, Malva JO, Bergelson JM, di Luca M, Schiavo G, Salinas S, Kremer EJ. Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity. J Neurosci. 2016 Sep 14;36(37):9558-9571.