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Yves De Koninck laboratory
Affiliated with Université Laval & CERVO Research Centre
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Annie Castonguay, PhD
Annie.Castonguay.phd@gmail.com
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ORCID:
Annie Castonguay
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Published articles
Alumnus
Years in the YDK lab:
2006-2022
Current position:
Conseillère stratégique, Direction de la recherche et de l'innovation en enseignement supérieur, ministère de l'Enseignement supérieur
Recent publications
Recent publications from the YDK lab are listed here
Dong W, Jin SC, Allocco A, Zeng X, Sheth AH, Panchagnula S, et al.
Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia.
iScience. 2020;23(10):101552.
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Ferrini F, Perez-Sanchez J, Ferland S, Lorenzo L-, Godin AG, Plasencia-Fernández I, et al.
Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization.
Nat Commun. 2020;11(1):3935.
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Castonguay A, Lorenzo L-, Wiseman PW, Ribeiro-da-Silva A, De Koninck Y, Godin AG.
Revealing Abnormal Oligomerization of Proteins in Single Cells
.. 2019;116(3, Supplement 1):426a.
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Richner M, Pallesen LT, Ulrichsen M, Poulsen ET, Holm TH, Login H, et al.
Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain.
Sci Adv. 2019;5(6):eaav9946.
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Gagnon M, Bergeron MJ, Perez-Sanchez J, Plasencia-Fernández I, Lorenzo L-, Godin AG, et al.
Reply to The small molecule CLP257 does not modify activity of the K-Cl co-transporter KCC2 but does potentiate GABA receptor activity.
Nat Med. 2017;23(12):1396-1398.
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Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, et al.
Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.
Neuropsychopharmacology. 2016;41(4):949-59.
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Miraucourt LS, Tsui J, Gobert D, Desjardins J-, Schohl A, Sild M, et al.
Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells.
Elife. 2016;5.
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Taylor AM, Castonguay A, Taylor AJ, Murphy NP, Ghogha A, Cook C, et al.
Microglia disrupt mesolimbic reward circuitry in chronic pain.
J Neurosci. 2015;35(22):8442-50.
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Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, et al.
Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.
J Neurosci. 2015;35(15):6057-67.
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Bergeron MJ, Castonguay A, De Koninck Y.
[KCC2: a new therapeutical target for the treatment of neurological diseases].
Med Sci (Paris). 2014;30(5):514-7.
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Thériault G, Cottet M, Castonguay A, McCarthy N, De Koninck Y.
Extended two-photon microscopy in live samples with Bessel beams: steadier focus, faster volume scans, and simpler stereoscopic imaging.
Front Cell Neurosci. 2014;8:139.
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Gagnon M, Bergeron MJ, Lavertu G, Castonguay A, Tripathy S, Bonin RP, et al.
Chloride extrusion enhancers as novel therapeutics for neurological diseases.
Nat Med. 2013;19(11):1524-8.
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Ferrini F, Trang T, Mattioli T-, Laffray S, Del'Guidice T, Lorenzo L-, et al.
Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.
Nat Neurosci. 2013;16(2):183-92.
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Caillier B, Pilote S, Castonguay A, Patoine D, Ménard-Desrosiers V, Vigneault P, et al.
QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile.
Fundam Clin Pharmacol. 2012;26(5):599-608.
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Doyon N, Prescott SA, Castonguay A, Godin AG, Kröger H, De Koninck Y.
Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis.
PLoS Comput Biol. 2011;7(9):e1002149.
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