Research in the Yves De Koninck laboratory – YDK lab – aims to understand normal and altered transmission of signals between neurons (synaptic transmission). The YDK lab uses and develops state-of-the-art imaging, electrophysiological and computational approaches to better understand the brain and nervous system. Our research has provided insight in the mechanisms underlying chronic pain, drug dependence, epilepsy, Alzheimer's disease and cognitive decline associated with aging, and led to the identification of drug targets to treat these disorders.
